Surrogate insulin-producing cells
نویسندگان
چکیده
منابع مشابه
Surrogate insulin-producing cells
Diabetes, a large and growing worldwide health concern, affects the functional mass of the pancreatic beta cell, which in turn affects the glucose regulation of the body. Successful transplantation of cadaveric islets and pancreata for patients with uncontrolled type 1 diabetes has provided proof-of-concept for the development of commercial cell therapy approaches to treat diabetes. Three broad...
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Cellular replacement offers the potential of a `cure` for type 1 diabetes mellitus. Shortage of suitable donors limits widespread implementation of this approach. Recent research has been focused on potential new sources of beta-cells including embryonic and adult stem cells, and other organs cells. The contribution of beta-cell replication to new islet formation, in addition to the potential f...
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ژورنال
عنوان ژورنال: F1000 Medicine Reports
سال: 2012
ISSN: 1757-5931
DOI: 10.3410/m4-15